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Cover of Prescription: Murder
On the shelf

Prescription: Murder

1968Age guide: 12+

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Checked 11 Nov 2026 · Data: JustWatch

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In Columbo's first outing, a psychiatrist uses a patient he is having an affair with to help him kill his wife, but his perfect alibi may come apart at the hands of a seemingly befuddled LAPD…

★ 7.7/10 · 43 TMDB audience ratings

Starring

  • Peter FalkColumbo
  • Gene BarryRay Flemming
  • Katherine JusticeJoan Hudson
  • William WindomBurt Gordon
  • Nina FochCarol Flemming
  • Virginia GreggMiss Petrie
  • Andrea KingCynthia Gordon
  • Susanne BentonBlonde
Image from Prescription: MurderImage from Prescription: Murder
Audience reviews from TMDB · may contain spoilers

Wuchak: “Prescription: Murder” (1968) PLOT: An arrogant, nonchalant psychiatrist (Gene Barry) murders his wife and uses his naïve actress girlfriend to get away with… Read full review

GenerationofSwine: As far as detectives go, Columbo is my guy. He's the wrinkled low expectation mess that uses his appearance and working class persona… Read full review

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